4th ACTC | Advances in Circulating Tumor Cells | Liquid Biopsy: Latest Advances and Future Challenges

Main Topics

MAIN TOPICS

Latest developments on:

  • Circulating Tumor Cells (CTCs)
  • Circulating tumor DNA (ctDNA)
  • Circulating miRNAs (cfmiRNAs)
  • Exosomes and extracellular vesicles (EVs)
  • Tumor-educated platelets (TEPs)

Novel and established technologies in liquid biopsies:

  • CTC isolation and detection systems
  • Single cell analysis
  • Single cell drug testing
  • CTC-derived explants (CDX)
  • Organ-on-a-chip technology
  • Epigenetic signatures

Clinical Applications on:

  • Early detection
  • Detection of minimal residual disease
  • Cancer screening for patient selection
  • Monitoring treatment response and drug resistance
  • Liquid biopsy as a treatment-selection tool in advanced cancers
  • Clinical trials

Implementation in clinical practice:

  • Pre-analytical considerations, quality control
  • Standardizing Liquid Biopsy for clinical use
  • International Public-Private Partnerships on liquid biopsy
  • Regulatory Considerations for Utilizing Liquid Biopsies in Drug and Diagnostics Development

4th ACTC | Advances in Circulating Tumor Cells | Liquid Biopsy: Latest Advances and Future Challenges